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NV Plumping


1. Ative Ingredients

Sesamum Indicum Seed Extract;

Hyaluronic Acid.

2. Benefits

Lip filling and volume;

Reduction of expression lines;

Combats sagging;

Enhances and restores facial volume and regions such as cheekbone and lip contour;

Smoothing of the "perioral" lip lines (creases that form on the edges of the lips);

Anti-aging treatment for the hands;

Improves skin elasticity;

Antioxidant action;

Firmer skin;

Promotes restoration and hydration for the hair.

3. Usage

Anhydrous bases (water-free): stick products (sunscreen, lipsticks, deodorant, etc);

Non-ionic, anionic and cationic emulsions;

Gels and cream gels.

4. Properties

Produto Cruelty free
Cruelty Free


The encapsulation of Sesamum Indicum Seed Extract in hyaluronic acid nanoparticles through Nanovetores Technology enables intelligent and safe delivery of the active ingredient, with a significant increase in stability, ensuring greater efficiency of cosmetic products.

NV Plumping nanoparticles are characterized by having an average size greater than 200nm. Encapsulation through the technology developed by Nanovetores allows the stabilization of sensitive and complex components to be formulated in their free form. The blend can be incorporated into cosmetic formulations, where it enhances and restores facial volume in regions such as cheekbone and lip contouring, improves hydration, and reduces expression lines and sagging. The natural characteristics and non-toxicity of the product enable its daily use, delivering efficacy safely.


Mechanism of Action

Nv Plumping presents the benefits of the nano encapsulated active, such as active protection, the best permeation that ensures effective action in the target. Sesamine encapsulated in hyaluronic acid nanoparticles promotes a synergistic effect for the increase of lip and facial volume, conferring youthful, harmonic, and natural aspects.

The action of NV Plumping consists of the activation of the first phases of adipogenesis to obtain at the end a greater number of mature adipocytes capable of synthesizing and accumulating fat. When the early stages of terminal differentiation of preadipocytes are stimulated, the aging process of adipose tissue can be reversed and the consequences of subcutaneous fat loss may be reduced. Thus, NV Plumping can act as a linker or agonist of PPARγ and activate it, stimulating the passage from pre-adipocyte to adipocyte to finally have more mature adipocytes, capable of synthesizing and accumulating fats.



Sesamum indicum seed extract is rich in sesamine, which belongs to a group of compounds called lignans. Lignans are a type of polyphenol found in plants. Research shows that sesame oil is able to increase the expression of PPARγ and that sesamine itself increases the transcriptional activity of PPAR γ in various cell types. These activities can be explained with the activation of the Gamma PPAR receptor, since its direct involvement in all these processes has been demonstrated. These studies support the mechanism described for the stimulation of sesamine adipogenesis.


Hyaluronic acid (Figure 3) is a substance naturally present in the human body, responsible for decreasing the rate of water evaporation for the maintenance of the skin natural hydration, besides being a collagen-stimulating substance. Hyaluronic acid has a high ability to bind to the water molecule forming a cohesive block. It functions as a humectant agent and keeps water molecules on the surface of the skin to keep it hydrated. Prevents TEWL (Transepidermal Water Loss), keeping the skin hydrated, ensuring that water does not escape from the skin surface. Topical application of acid, due to this ability to form a cohesive block with water, decreases the appearance of expression lines and wrinkles, enhances and restores facial volume, making the skin smoother, firmer, and rejuvenated. The active also has an antioxidant effect, because it acts as a scavenger of free radicals, increasing the protection of the skin in relation to radiation and contributing to the increase of tissue repair capacity.

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