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FACIAL

NV Niacinamide

Features

1. Ative Ingredients

Niacinamide.

2. Benefits

Skin barrier regeneration;

Cellular renewal;

Photoaging prevention;

Blue light protection;

Acne vulgaris treatment;

Antioxidant properties;

Standardizes skin tone and reduces pallor;

Adjuvant in the care of atopic dermatitis and rosacea.

3. Usage

Primers;

Creams;

Masks;

Serums;

Gels;

Face and eye cream gels;

Liquid soaps;

Makeup removers;

Skin tone standardizing products.

4. Properties

Vegano
Vegan
Produto Cruelty free
Cruelty Free
Cdial Halal
Cdial Halal

NV NIACINAMIDE

The Niacinamide encapsulation through Nanovetores Technology enables the smart and safe delivery of the active ingredient, with a significant increase in stability, ensuring greater cosmetic products efficiency.

NV Niacinamide nanoparticles are characterized by an average size greater than 200 nm. In addition to safety, they offer active protection against hydrolysis, common to carbonyl structures, such as Niacinamide. Another advantage of NV Niacinamide is the substance skin permeation improvement , which reaches the dermis in its active form, without loss through degradation. 

With greater compatibility with chemical ingredients and reduced irritant effects such as burning, itching, and erythema, NV Niacinamide is a superior alternative for cosmetic formulations.

Mechanism of Action

The effect of niacinamide on the skin surface structure can be seen to improve its appearance, including reduction of fine lines and wrinkles, hyperpigmented spots, paleness, and improved skin elasticity. Since NADH and NADPH are antioxidants, a possible effect of topically applied niacinamide is to increase the levels of these antioxidants and consequently to inhibit oxidative processes, such as collagen glycation. These oxidative processes play a significant role in skin aging, in addition to impacting the yellowish or pale appearance of the skin, due to the Maillard reaction, which forms yellow compounds . Niacinamide increases the rate of cell renewal and has a stimulating effect on the synthesis of collagen, keratin from epidermal biopolymers (proteins), filaggrin, and involucrin. Decreased skin pigmentation can also be observed by the suppressive effect of niacinamide, transfer of melanosomes from melanocytes to keratinocytes, and photoprotective effect related to the reduction of oxidative stress, reducing damage caused by blue light.

In the treatment of acne vulgaris, niacinamide can contribute with its seborregulatory effect, anti-inflammatory and curative properties, decrease in the number of pustules, comedones, and papules. It significantly reduces the expression of inflammatory mediators produced by keratinocytes such as: IL-6, IL-10, MCP-1, and TNF-a mRNA responsible for tissue damage. Furthermore, niacinamide may exert direct control over Propionibacterium acne as a result of inhibition of Sir2 10,11,12 enzymes. Due to its numerous benefits, niacinamide has proved to be a versatile active for cosmetic application

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Nanovetores is a company that produces high performance active ingredients for pharmaceutical and cosmetic industries. 

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